• Anticancer drugs
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Records 61 to 80 of 168
 
Genomics of Drug Sensitivity in Cancer
Targets
Target pathway
Download molecule
Cluster number
calculated LogS
Molecular weight
calculated LogP
Ro5 violations
Quizartinib FLT3 RTK signaling 24889392 47 -5,721 560,677 4,7979 1
PI-103 PI3Kalpha, DAPK3, CLK4, PIM3, HIPK2 PI3K/MTOR signaling 9884685 96 -5,694 348,361 2,5871 0
KU-55933 ATM Genome integrity 5278396 119 -5,621 395,502 4,8128 0
GNF-2 BCR-ABL ABL signaling 5311510 117 -5,605 374,321 3,9147 0
AZD8055 MTORC1, MTORC2 PI3K/MTOR signaling 25262965 36 -5,601 465,552 2,4865 0
Ispinesib Mesylate KSP Mitosis 6450816 109 -5,598 517,071 4,7721 1
FTI-277 Farnesyl-transferase (FNTA) Other 3005532 122 -5,597 447,622 2,2993 0
KIN001-244 PDK1 (PDPK1) Other, kinases 56965967 18 -5,569 516,503 2,2408 1
CMK RSK2 ERK MAPK signaling 16663089 57 -5,553 358,828 2,1669 0
CX-5461 RNA Polymerase 1 Other 25257557 37 -5,524 513,624 1,9594 1
BMS-509744 ITK Other 20635522 52 -5,504 609,814 5,3672 2
Afatinib ERBB2, EGFR EGFR signaling 10184653 11 -5,476 485,946 3,6354 0
Bosutinib SRC, ABL, TEC Other, kinases 5328940 115 -5,461 530,454 4,5762 1
OSI-027 MTORC1, MTORC2 PI3K/MTOR signaling 44224160 34 -5,375 406,445 -3,0368 0
Fedratinib JAK2 Other, kinases 16722836 55 -5,375 524,688 4,9144 1
CAY10603 HDAC1, HDAC6 Chromatin histone acetylation 24951314 46 -5,364 446,502 3,2536 0
BI-2536 PLK1, PLK2, PLK3 Cell cycle 11364421 75 -5,348 521,664 3,239 1
A-443654 AKT1, AKT2, AKT3 PI3K/MTOR signaling 10172943 86 -5,274 397,481 2,7787 0
Crizotinib MET, ALK, ROS1 RTK signaling 11626560 66 -5,264 450,344 3,5382 0
RO-3306 CDK1 Cell cycle 44450571 33 -5,244 351,453 2,9502 0
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Records 61 to 80 of 168
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