• Anticancer drugs
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Records 41 to 60 of 168
 
Genomics of Drug Sensitivity in Cancer
Targets
Target pathway
Download molecule
Cluster number
calculated LogS
Molecular weight
calculated LogP
Ro5 violations
Paclitaxel Microtubule stabiliser Mitosis 36314 138 -6,289 853,915 3,188 2
GSK1070916 AURKA, AURKC Mitosis 46885626 29 -6,278 507,64 3,781 1
Avagacestat Amyloid beta20, Amyloid beta40 Other 46883536 2 -6,256 520,89 3,4173 1
OSI-930 KIT RTK signaling 9868037 98 -6,25 443,448 5,1538 1
IPA-3 PAK1 Cytoskeleton 521106 127 -6,184 350,461 5,4798 1
BAY-61-3606 SYK Other, kinases 10200390 85 -6,17 390,402 1,9877 0
CGP-082996 CDK4 Cell cycle 24825971 48 -6,084 456,592 4,6327 0
Bryostatin 1 PKC Other, kinases 5280757 103 -6,078 905,04 5,0065 3
Idelalisib PI3Kdelta PI3K/MTOR signaling 11625818 67 -6,049 415,431 2,858 0
I-BET-762 BRD2, BRD3, BRD4 Chromatin other 46943432 26 -6,022 423,903 2,9219 0
Alectinib ALK RTK signaling 49806720 25 -6,018 482,626 4,7668 0
NVP-TAE684 ALK RTK signaling 16038120 58 -5,955 614,213 4,599 1
Pazopanib CSF1R, KIT, PDGFRA, PDGFRB RTK signaling 10113978 87 -5,921 437,527 1,7881 0
BMS-536924 IGF1R, IR IGFR signaling 10390396 9 -5,895 479,966 1,628 0
Amuvatinib KIT, PDGFRA, FLT3 Other, kinases 11282283 79 -5,876 447,518 3,8291 0
BMS-754807 IGF1R, IR IGFR signaling 24785538 49 -5,859 461,504 2,3302 0
Nutlin-3a (-) MDM2 p53 pathway 11433190 72 -5,847 581,498 5,4649 2
Pelitinib EGFR EGFR signaling 6445562 111 -5,818 467,931 4,0385 0
Docetaxel Microtubule stabiliser Mitosis 148124 138 -5,811 807,887 2,609 2
A-770041 LCK, FYN Other, kinases 9549184 102 -5,744 621,744 3,8335 2
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Records 41 to 60 of 168
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