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Genomics of Drug Sensitivity in Cancer
Targets
Target pathway
Download molecule
Cluster number
calculated LogS
Molecular weight
calculated LogP
Ro5 violations
Gemcitabine Pyrimidine antimetabolite DNA replication 60750 144 -1,578 263,199 -2,0433 0
Mitomycin-C DNA crosslinker DNA replication 5746 149 -1,378 334,331 -1,8035 0
NSC-87877 SHP-1 (PTPN6), SHP-2 (PTPN11) Other 5459322 113 -1,298 459,458 0,7371 0
Cytarabine Antimetabolite DNA replication 6253 144 -0,731 243,218 -3,0346 0
Cisplatin DNA crosslinker DNA replication 84691 141 -0,53 195,08 0 0
Bortezomib Proteasome Protein stability and degradation 387447 130 0,031 384,242 1,9321 0
DMOG HIF-PH Metabolism 560326 126 0,043 175,139 -1,6359 0
AICA Ribonucleotide AMPK agonist Metabolism 65110 144 0,379 338,212 -6,1716 2
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