|
Gemcitabine
|
Pyrimidine antimetabolite
|
DNA replication
|
60750
|
144
|
-1,578
|
263,199
|
-2,0433
|
0
|
|
Mitomycin-C
|
DNA crosslinker
|
DNA replication
|
5746
|
149
|
-1,378
|
334,331
|
-1,8035
|
0
|
|
NSC-87877
|
SHP-1 (PTPN6), SHP-2 (PTPN11)
|
Other
|
5459322
|
113
|
-1,298
|
459,458
|
0,7371
|
0
|
|
Cytarabine
|
Antimetabolite
|
DNA replication
|
6253
|
144
|
-0,731
|
243,218
|
-3,0346
|
0
|
|
Cisplatin
|
DNA crosslinker
|
DNA replication
|
84691
|
141
|
-0,53
|
195,08
|
0
|
0
|
|
Bortezomib
|
Proteasome
|
Protein stability and degradation
|
387447
|
130
|
0,031
|
384,242
|
1,9321
|
0
|
|
DMOG
|
HIF-PH
|
Metabolism
|
560326
|
126
|
0,043
|
175,139
|
-1,6359
|
0
|
|
AICA Ribonucleotide
|
AMPK agonist
|
Metabolism
|
65110
|
144
|
0,379
|
338,212
|
-6,1716
|
2
|